Neuronal synapses (chemical)
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Neuronal synapses (chemical)
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Khan AcademySal Khan
The GABA-B receptor functions as a neuronal inhibitor, distinct from its counterpart, the GABA-A receptor. It operates as a G-protein-coupled receptor (GPCR), meaning that upon activation, it initiates a cellular signaling cascade rather than acting as a direct ion channel. When a signal molecule binds, the receptor releases its associated G-protein. The G-beta-gamma subunit then travels through the cell to activate a specific type of potassium channel called GIRK (G-protein-gated inwardly recti
2:56
The GABA-B receptor functions as a neuronal inhibitor, distinct from its counterpart, the GABA-A receptor. It operates as a G-protein-coupled receptor (GPCR), meaning that upon activation, it initiates a cellular signaling cascade rather than acting as a direct ion channel. When a signal molecule binds, the receptor releases its associated G-protein. The G-beta-gamma subunit then travels through the cell to activate a specific type of potassium channel called GIRK (G-protein-gated inwardly recti
103.4K views6 months ago
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GABA (neurotransmitter): what it is and what role it plays in the brain
GABA (neurotransmitter): what it is and what role it plays in the brain
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