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Controlling ribosomal RNA could help researchers target diseases driven by too little or too much protein production.
Introduction Patients with SLE have an increased risk of infections and infection-related mortality, which may be associated ...
Hiroshima University researchers have demonstrated a proof of concept for the mass production of genome-edited T cells that ...
A woman who had three different autoimmune conditions has not required treatments for almost a year after her immune cells were genetically modified and used to kill off the rogue cells attacking her ...
In desperation, the woman’s care team reached out to Müller, a hematologist-oncologist at the University Hospital of Erlangen, a roughly three-hour drive away by ambulance. In recent years, he and his ...
A CAR-T cell therapy has successfully treated not one, not two, but three different autoimmune diseases at once in a patient, providing further proof of the modality’s promise in the disease area as a ...
In a new study published in Science titled, “Mitochondrial metabolism and signaling direct dendritic cell function in antitumor immunity,” researchers from St. Jude Children’s Research Hospital have ...
For years, one of the most powerful weapons against certain blood cancers, called CAR-T therapy, has required an elaborate process: Doctors extract a patient’s immune cells, ship them to a specialized ...
Manufacturing CAR T cell therapy—one of the most powerful weapons against certain blood cancers—has to date involved an elaborate process, through which doctors first extract a patient’s immune cells ...
The study, “Integration of phospho-signaling and transcriptomics in single cells reveals distinct Th17 cell fates,” was published in Cell Reports. In the study, first author Seth Fortmann, M.D., Ph.D.