When activated by its target, the newly characterized molecule rips the genome apart, a lethal move that researchers can ...

R-loops, three-stranded RNA–DNA hybrids, naturally form during gene activity and DNA repair. In balance, they help regulate genes and maintain genome stability; when uncontrolled, they can damage DNA ...

Scientists from Skoltech and the University of Potsdam have developed a physical theory that sheds light on how molecular motors organize the three-dimensional structure of the genome. Using ...

A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential than researchers realized. Scientists at Scripps Research have discovered ...

Oxidative stress-induced DNA damage potentiates accumulation of R-loops, DNA:RNA hybrid structures with a displaced DNA strand that are resolved in a poly (ADP-ribose) (PAR)-dependent manner via PARP ...

Most people will know ekwb for its extensive custom watercooling hardware. The company recently developed an AIO, too - and today James looks at both the 240mm and 360mm versions. Has ekwb got what it ...

The annual meetings of the Chicago Loop Alliance are no place for truth-telling about the self-evident problems of the Chicago Loop. As Friday’s big gathering at Willis Tower made clear, this is a ...

In late January, The Loop at the Eastgate Crossin g shopping center in Chapel Hill reopened its doors. The restaurant announced in July 2025 that it had to close due to flood damages caused by ...

CHAPEL HILL, N.C. (WTVD) -- The Loop is back and officially open for business. The popular restaurant within Chapel Hill's Eastgate Crossing had been shuttered since July as a result of flooding ...

An R-loop is a three-stranded nucleic acid structure that serves as a transcriptional intermediate, consisting of an RNA-DNA hybrid and a displaced single-stranded DNA (ssDNA). Small RNAs are RNA ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key repair process called homologous recombination, the cell uses loops in its ...

A new fluorescent sensor is giving scientists an unprecedented view of how cells respond to DNA damage, capturing the repair process as it unfolds in real time. The tool, developed at Utrecht ...