A study has revealed that a pressure-sensing protein known as Piezo1 plays a critical role in supporting gut health. The study's findings may unlock new routes for understanding and treating complex ...
(A, B) The qRT-PCR results showed increased mRNA expression of HBEGF, EREG, and AREG induced by Yoda1 in endothelial cells and was reversed with Piezo1 knockdown in HUVEC cells. (C, D) the ELISA assay ...
Gut enterochromaffin cells regulate gut and bone homeostasis via serotonin production. A recent report suggested that gut microbes regulate serotonin levels, but the underlying molecular mechanisms ...
A new study reveals how mechanical forces and tissue mechanics influence the morphology of the developing brain, and establishes a direct link in neural stem cells between Piezo1, a ...
A study by scientists at Harvard Medical School and the Icahn School of Medicine at Mount Sinai has revealed how a pressure-sensitive protein, PIEZO1, helps regulate intestinal motility and control ...
The ability to sense mechanical stimuli, like touch or blood pressure, is essential to physiological processes in humans and across the animal kingdom. In a new study, Scripps Research scientists show ...
The brain is the softest organ of the body, so when rigid Aβ plaques form, they stand in stark contrast to the squishiness surrounding them. Microglia sense this rigidity via Piezo1, a calcium channel ...
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