Using human liver samples and a mouse model of cirrhosis, researchers identified epigenetic overactivation of the inflammatory PAF–PAF-R pathway in hepatic macrophages as a key driver of liver damage.

Fats are an important part of the human diet as a major source of energy. Around 90% of the fat stores are on top of muscle, so just under the skin. However, excessive dietary fat intake leads to fat ...

Many liver diseases share a common characteristic: fibrosis, the progressive accumulation of scarring in the liver tissue.

New genetic map of the human liver reveals why certain areas are more susceptible to fatty liver disease while others are ...

If scientists could shrink themselves to microscopic size and take a journey through the human body—like the submarine crew in the 1966 science fiction classic "Fantastic Voyage"—one of their first ...

The liver stands as a powerhouse organ, orchestrating a symphony of crucial functions essential for our overall health. It serves as the body’s primary detoxifier, meticulously removing harmful ...

Never-before-seen 3D reconstructions of human liver tissue have been created at a cellular level. The details obtained by a team of UW Medicine and University of Washington engineers and physicians ...

The liver and pancreas are organs in the upper abdomen. The liver is vital for metabolism, detoxification, digestion, and more. The pancreas produces essential enzymes and hormones. Together, they ...