Researchers have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ribosomes as they convert mRNA into proteins. The ...

Ribosomes are fundamental molecular machines that translate mRNA sequences into polypeptides, ensuring the proper synthesis of proteins essential to cellular function. However, the fidelity of protein ...

Scientists report a method for stable attachment of peptides to tRNAs, which has allowed them to gain new fundamental insights into ribosome function by determining the atomic-level structures of ...

A new technique reveals ribosome cooperativity, providing new insights into protein production. Researchers from Marvin Tanenbaum’s group at the Hubrecht Institute (Utrecht, Netherlands) have ...

Researchers from the Tanenbaum group at the Hubrecht Institute have developed a new microscopy technique to observe how ...

Intracellular machines called ribosomes use messenger-RNA sequences to synthesize proteins. Investigations using single-molecule imaging and cryo-electron microscopy techniques reveal structural and ...

Proteins are the key players that regulate cellular structure and function. DNA, which functions as the blueprint for protein synthesis, is first transcribed into a messenger RNA (mRNA), which is ...

Aging leads to a decline in cellular fitness and loss of optimal protein function. The mechanisms underlying how aging causes proteins to aggregate have not been fully understood. Using models of ...

At one time or another, most of us have played with a flipbook, using our thumbs to rapidly flip a series of pictures to create an illusion of movement. Scientists use a similar technique to study the ...

These spots are socRNAs being translated by ribosomes in a cell. They get brighter over time, showing active translation. The complex, which includes the socRNA and ribosome, is attached to the plasma ...