A study reveals chromatin moves in constrained or freer patterns, shaping how genes contact regulatory elements and repair ...

This study analyzes the temporal dynamics of gene expression following TNF stimulation in macrophages. The work brings valuable data and new methodological approaches to implicate the splicing rate of ...

Virginia Tech scientists at the Fralin Biomedical Research Institute say the increased risk of cardiovascular disease after ...

Understanding how genes are switched on and off in specific cell types remains one of biology's central challenges. While AI has made major progress in decoding the regulatory logic of DNA, applying ...

From the TATA box to alternative splicing and noncoding RNAs, scientists are uncovering the intricate choreography that controls gene expression. These molecular mechanisms determine when, where, and ...

A new technique shows DNA binding domains are not central to transcription factor targeting in human cells, unlike in ...

Using CRISPR, multiomics, and machine learning, molecular biologist Larschan unravels the mysteries of the X chromosome.

Groundbreaking Phase 1/2a clinical trials co-led by Linda Laux, MD, from Ann & Robert H. Lurie Children’s Hospital of Chicago, show that the first gene regulation treatment for epilepsy is safe and ...

From DNA’s tightly packed chromatin to the precise on/off switches in regulatory sequences, scientists are uncovering how cells fine-tune gene expression. New research reveals surprising roles for ...

Gene regulation timing, controlled by non-coding DNA elements, drives limb development, with disruptions leading to distinct defects, highlighting new mechanisms behind birth abnormalities.