As common as depression is—about one person in 10 experiences depression in any given year—it still eludes complete understanding. There does not seem to be a single cause; rather many factors ...

A large international study led by researchers at the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, shows that major depressive disorder (MDD) not only increases risk ...

The core experiences of depression — changes in energy, activity, thinking, and mood — have been described for more than 10,000 years. The word “depression” has been used for about 350 years. Given ...

In a major scientific breakthrough, scientists have identified two specific types of brain cells linked to depression for the first time, offering a clearer biological understanding of the disorder.

Depression, recognized as the leading cause of disability worldwide, affects nearly one in six people over their lifetimes. Despite decades of research, much remains unknown about the biological ...

You spot signs of depression in someone you care about or in yourself and want a clear explanation. Research still shows no single cause, but scientists now point to a mix of genes, brain-cell changes ...

Clinical depression is often linked to aches and pains, including back pain. Having chronic back pain is also associated with worsening depression symptoms in some people. Research indicates there’s a ...

Avolition refers to a severe reduction in self-initiated drive that makes starting or finishing everyday tasks feel overwhelming or impossible, even when you recognize their importance or want to ...

Objective: We sought to examine whether higher rates of depression in women than in men can be explained partially by the artifact hypothesis, which suggests that when both sexes have the same ...

Depression and seasonal affective disorder (SAD) share similar symptoms, but depression can occur at any time of the year, while SAD follows a recurring seasonal pattern. For a SAD diagnosis, a person ...