There are some 80 human diseases that in one way or another are considered autoimmune. Perhaps the most common indication of an autoimmune pathogenesis is the presence of circulating antibodies that ...

The immune system defends the body against a wide range of internal and external threats. However, this versatility becomes an issue when immune mechanisms target host cells instead—a phenomenon ...

An expert discusses how rilzabrutinib, a recently FDA-approved Bruton tyrosine kinase (BTK) inhibitor, targets the autoimmune pathophysiology of immune thrombocytopenia (ITP) by modulating B cells, ...

Hepatoblasts differentiate into hepatocytes, large and small cholangiocytes. CK8, CK18, and CK19 are expressed in hepatoblasts. CK8 and CK18 are expressed in hepatocytes at week 6. CK19 is expressed ...

Osaka, Japan – We all know that a strong immune system is a definite advantage. Yet, sometimes, the immune system goes awry and attacks one’s body. This autoimmunity is the cause of various disorders, ...

Autoimmune diseases are thought to be the result of mistaken identity. Immune cells on patrol, armed and ready to defend the body against invading pathogens, mistake normal human cells for infected ...

A team identifies target protein regulating autoimmune disease lupus. A research team of Professor Yoontae Lee and Jiho Park, a PhD candidate, from the Department of Life Sciences at Pohang University ...

Visit NAP.edu/10766 to get more information about this book, to buy it in print, or to download it as a free PDF. Autoimmune diseases occur when the body’s immune system, which normally defends the ...

The Journal of Immunology reports that vaccination of neonatal mice with group A Streptococcus promoted a clonal expansion of innate-like B cells that produce antibody against N-acetyl-D-glucosamine, ...

In a recent study published in the Journal of Infection and Public Health, researchers reviewed the causes of diabetes mellitus (DM), focusing on respiratory viruses, including influenza virus and ...